Well, for the majority of people, no.
Now I don't want to get into a big long rant about about how HDL's & LDL's, often described as good and bad cholesterol, aren't even cholesterol at all, or that the test you get from your doctor doesn't actually measure LDL's, it just estimates it and I don't even want to get started on statins or those magical cholesterol lowering spreads.
Today I just want to focus on dietary cholesterol.
Firstly cholesterol, is essential for life and without it we would be dead, that's how important it is. We need about 3000 milligrams a day, which is 10 times the recommended daily allowance (RDA), or approximately 16 eggs. We don't get anywhere near enough cholesterol in our diet to stay alive, so it is the livers job to make up the difference, and that's exactly what it does, makes up the difference. The more cholesterol we eat, the less the liver needs to make, the less we eat, the more it needs to make, simples. One study found that eating 3 eggs a day, 3 times the RDA, with no dietary controls (meaning they could eat whatever else they wanted, so probably consuming more cholesterol), had little or no effect on cholesterol levels.
There is one exception to this and they are called hyperresponders. In the majority of the population (hyporesponders), dietary cholesterol has no effect on blood cholesterol, but in hyperresponders, diets high in cholesterol can increase blood cholesterol. Nobody really understands why, but even so the increase is relatively small, about 2.5mg per 100mg of additional dietary cholesterol, and it is not necessarily a negative increase, as increased LDL-1 particles are less likely to promote the formation of fatty deposits in your arteries.
So if you're eating a dozen eggs a week or 13oz of liver or less, you don't have anything to worry about, even if you are a hyperresponder.
I hope that clears up dietary cholesterol a bit, but if you do have any questions please feel free to comment below.